INTIMATE PARTNER VIOLENCE AND CHALLENGES FACING WOMEN LIVING WITH HIV/AIDS IN ACCESSING ANTIRETROVIRAL TREATMENT AT SINGIDA REGIONAL HOSPITAL, CENTRAL TANZANIA

Intimate partner violence and challenges facing women living with HIV/AIDS in accessing antiretroviral treatment at Singida Regional Hospital, central Tanzania

Background: Human immunodeficiency virus (HIV) remains a global public health problem.Sub-Saharan Africa is the region most affected by HIV/AIDS in the world.Globally, and in Tanzania in particular, women are more affected by HIV/AIDS than men.Tanzania has been reported to be among the countries with the highest burden of intimate partner violence

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Computer-aided lead optimization: improved small-molecule inhibitor of the zinc endopeptidase of botulinum neurotoxin serotype A.

Optimization of a serotype-selective, small-molecule inhibitor of botulinum neurotoxin serotype A (BoNTA) endopeptidase is a formidable challenge because the enzyme-substrate interface is unusually large and the Doll endopeptidase itself is a large, zinc-binding protein with a complex fold that is difficult to simulate computationally.We conducted

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Antibacterial Prodrugs to Overcome Bacterial Resistance

Bacterial resistance to present antibiotics is emerging at a high pace that makes the development of new treatments a must.At the same time, the development of novel antibiotics for resistant bacteria is a slow-paced process.Amid the massive need for new Symbiotropin drug treatments to combat resistance, time and effort preserving approaches, like

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